Objective?To investigate the correlation between low serum anti-müllerian hormone(AMH)and the clinical outcomes of frozen embryo transfer(FET)in the infertile women with diminished ovarian reserve(DOR).Methods?In this retrospective study,the clinical outcomes were followed in 256 patients with DOR undergoing FET cycles in the Department of Reproductive Medicine,Zhongda Hospital from January 2018 to June 2019.The possible influencing factors,including serum AMH,age,body mass index(BMI),duration of infertility,basal follicle stimulating hormone(FSH),basal estradiol(E2),endometrial thickness on the day of FET,embryo type(cleavage embryo/blastocyst),and the number of embryos transferred,were analyzed for evaluating the correlation with clinical outcomes of frozen embryo transfer.Results?A total of 386 cycles were included.The clinical pregnancy rate was 33.68%(130/386)and the abortion rate was 26.15%(34/130).The live birth rate was 16.05%(56/349)excluding 37 uncompleted followup pregnant cycles.In the comparison between clinical pregnant and non-pregnant groups,the female age of the clinical pregnancy group was obviously younger and basal FSH was significantly lower(P<0.05),but serum AMH level and thickness of endometrium on the day of FETin the clinical pregnancy group was obviously higher(P<0.05),and the proportion of blastocyst transferring was significantly higher(P<0.05).There were no significant differences of BMI,duration of infertility,basal E2 and number of transferred embryos between two groups(P>0.05).In the comparison of basic characteristics between abortion and live birth groups,the age of the live birth group was significantly younger(P<0.05).The patients were stratified into three groups based on AMH concentration:low(1.01 to 1.50 ng/mL),middle-low(0.51 to 1.00 ng/mL)and very-low(0.01 to 0.50 ng/mL)groups.The results of analysis revealed that the age,basal FSH,and embryo type in very-low AMH group were significantly different from those of the other two groups(P<0.05),but no significant difference of general information was found between the low AMH group and the middle-low group(P>0.05).In the terms of clinical outcomes,the clinical pregnancy rate of very-low AMH group was significantly lower than that of middlelow and low AMH group(P<0.05)while no significant difference of abortion rate and live birth rate was found among the 3 groups(P>0.05).The multiple logistic regression was used to further analyze the factors that might affect the clinical outcomes and the results revealed that the female age was the common factor having effect on clinical outcomes after adjustment for confounders.The clinical pregnancy rate and live birth rate were negatively correlated with age(P<0.05),and the abortion rate was positively correlated with female age(P<0.05).Blastocyst transferring could improve clinical pregnancy rate(P<0.05).Conclusion?Low AMH level is not associated with clinical outcomes of frozen embryo transfer in the patients with DOR,and serum AMH level can not predict the clinical outcomes of frozen embryo transfer.The main factor that affects the clinical outcomes should be the age of patients.The older the age of the patients,the lower the probability of clinical pregnancy and live birth,and the higher the risk of abortion.